a-Ethyl-aphenylgutarimide, 524 Ethyl xanthate
ammonia oxidation and, 626 2 Ethylamino-1,3,4 thiadiazole
leukemia and, 14 NAD'ase and, 14 N A D synthesis and, 14
polynucleotide synthesis and, 14 toxicity of,
nicotinamide and, 13 uric acid synthesis and, 13, 14
Ethylenebisdithiocarbamates—see nabam Ethylenediaminotetracetic acid—see
vers-ene
1,1' - Ethylene - 2,2' - dipyridylium di-bromide—see diquat
Ethylenethiuram monosulfide fungitoxicity of, 274 glucose metabolism and, 275 Ethylenethiourea
fungicidal action of, 278 Ethylenimines, 175
carcinogenic derivatives, 177
monofunctional derivatives, 177, 178 multifunctional derivatives, 177, 178 quinone derivatives, 177
Ethylphenylcarbamate cell division and, 250
a-Ethyltryptamine, 62, 63, 73, 90 Ethylurethan, 487, 518, 520, 621
ETM—see α-ethylenethiuram monosulfide Etryptamine—see a-ethyltryptamine Eutopic complexes, 60
Evipan, 520
Exercise tolerance tests, 549 FAD, 588
analogues of, 17 cyanide and, 395 structure of, 1
succinic dehydrogenase and, 480 Fatty Acids
cytochrome oxidase and, 443 oxidation of, arsenicals and, 105 production in mitochondria, 511 serum albumin and, 511 uncoupling by, 510
Ferbam—see dialkyldithiocarbamate fer
ric salt Fermentation
chlortetracycline and, 42 dialkyldithiocarbamates and, 270 oxytetracycline and, 42
Ferredoxin
carbon monoxide and, 610 Ferrichrome, 47
Ferricyanide, 475, 478, 586 ascorbic acid and, 579 growth and, 39
photophosphorylation and, 578 Fibrinokinase
extraction of, thiocyanate and, 361 Fibrogen, 464
Flagella
suramin and movement of, 292 Flavin adenine dinucleotide—see FAD Flavine mononucleotide—see F M N Flavinoids
chlorosis and, 253 Flavins
photophosphorylation and, 588 Flexner-Jobling carcinoma, 176 Fluoracetate, 491
acetate and, 492, 493 Fluoride
acid phosphatase and mechanism of ac
tion, 402, 403 enolase and, 401 calcification and, 360 catalase and, 385
chlorophyll metabolism and, 340 differential sensitivity to, 367 effects in vivo, 414-420 fermentation and, 419 glutamine synthetase and, 403
magnesium and, 366 hemoproteins and, 404
metalloenzymes and, 388, 403, 404, 405 nitrogen fixation and, 608
phosphatase and, 401, 402 phosphoglucomutase and, 401 phosphorylase and, 401, 402 pyrophosphatase and, 401, 402 succinic dehydrogenase and, 405 toxicity to plants, 338
Fluorine
bone metabolism and, 360 Fluoracetate
action of, 405
ammonium ions and, 494 blood sugar and, 493 brain respiration and, 493 citrate accumulation and, 492
radiation effects on, 645 convulsive effects of, 493 fluorocitrate and, 492 nitrogen fixation and, 494 Fluoroacetylcholine, 493 Fluoroacetyl CoA, 492
fluorocitrate synthesis and, 405 Fluoro analogues
inhibition of enzymes and, 405
Fluoroapatite fluorine and, 360
Fluorocitric acid, 405, 492, 493 5-Fluoronicotinamide
thiadiazole toxicity and, 14 0-Fluorooxalacetic acid, 490 Fluorosis, 360
FMN, 480, 581, 582, 586, 588
photosynthesis and, 567, 568, 575, 576 Formate
catalase and, 385
hydrogen production from, 598 nitrification and, 621
purine synthesis and, 41 Formylglycinamide ribotide
azaserine and, 41 Formylglycinamidine
azaserine and, 41 ΛΓ-Formylmelphalan, 169 N-Formylmelphalan amide, 170 iV-Formylmelphalan ethyl amide, 170 Ν - Formylsarcolysylphenylalanine ethyl
ester, 170 Fowler's solution, 287 Frequentin
production in soil, 26 0-Fructofuranosidase
metal sensitivity of, 371 Fructokinase
monovalent cations and, 367, 368 Fructose 1,6-diphosphatase
quinones and, 148 Fructose 1,6-diphosphate
metabolism of polyene antibiotics and, 40
Fructose oxidation fluoride and, 415 Fumarase, 450, 451, 452
acid dyes and, 488 activation of, 488
competitive inhibitors of, 489 distribution of, 488
inhibition by sulfonates, 447 radiation and, 643
suramin and, 293 thiocyanate and, 381 trypanocides and, 489 Fungicides, 263-282
dialkyldithiocarbamates, 270-273 dithiocarbamates, 269-276
heterocyclic nitrogen compounds, 278, 279
metals, 264-266 nabam group, 273-276 quinones, 145, 276, 277 sulfur, 266-269 Fungitoxicity
metal ions and, 325, 326 6-Furfurylaminopurine—see kinetin Galactoflavin, 90
Galactosamine, 32 Galactose, 32 iS-Galactosidase
aromatic diamidines and, 296 suramin and, 293
Gamma rays
oxidative phosphorylation and, 644 relative biological efficiency of, 637 thymidine incorporation and, 638 urease and, 634
Gas transport
inhibitors of, 539-556 Gas-transporting capacity, 542 Ghosts of cells
polymyxin and, 38 Gibberellins, 245
mechanism of action, 250 Gladiolic acid
production in soil, 26 Glaucoma
organophosphates, carbamates and, 206 Gliotoxin
nucleic acid synthesis and, 44 production in soil, 26 protein synthesis and, 44 Globin, 456
radiation and synthesis of, 636 succinic oxidase and, 411 Globulin
salts and solubility of, 362 /3-Globulin, 480
Ghmerella cingulata toxicity of sulfur and, 328 Glucosamine
cell membranes and, 37 cell wall structure and, 35 deamination of, 419
occurrence of, in mucopolysaccharides, 32
Glucose
hydrogen production and, 598 metabolism of
aromatic diamidines and, 296 arsenicals and, 104
comparative effects of nabam and methylisothiocyanate, 275 fluoride and, 415
suramin and, 292 nitrification and, 620
occurrence in mucopolysaccharide, 32 Glucose dehydrogenase
quinones and, 152
Glucose-6-phosphate dehydrogenase cobalt and, 336
comparative action of fungicides on, 275 deoxyNAD and, 16
dialkyldithiocarbamates and, 270 sulfhydryl binding agents and, 104 /3-Glucosidase, 447
/3-Glucuronidase
polyanionic inhibitors and, 450-463 scheme of activation and inhibition, 462 Glutamic acid
accumulation of
chloramphenicol and, 43 chlortetracycline and, 44 oxytetracycline and, 44 cell walls and, 33, 35 cycloserine and, 45
formylglycinamidine synthesis and, 41 intracellular concentration of, 37 N A D synthesis and, 3
nitrogen fixation and, 607
occurrence in mucopolysaccharides, 32 oxidation of, 104
synthesis in brain, 483 Glutamic acid decarboxylase
kinetics of mercaptide formation and, 130, 131
Glutamic acid dehydrogenase combination with silver, 125 deoxyNAD and, 17
inhibition by mercurials, 126 Glutamic acid polypeptide
chloramphenicol and, 43 Glutamic-oxaloacetic transaminase
arsenicals and, 105
Glutamic-pyruvic transaminase arsenicals and, 105
Glutaminase
quinones and, 148 Glutamine
azaserine, DON and, 5, 41 N A D synthesis and, 3 synthesis of, 525, 530
in brain, 483
transglutaminase and, 55 Glutamine synthetase
alternative activating metals of, 365, 366 fluoride and, 403
Glutamine transferase
alternative activating metals of, 365, 366 Glutaric acid, 486
Glutathione
arsenosobenzenes and, 101 extraction of enzymes and, 362
dialkyldithiocarbamate inhibitions and, 270
inhibition of enzymes by quinones and, 146
lewisite complex of, 109
mercury toxicity in plants and, 348 methemoglobin and, 552
myleran and, 185
photophosphorylation and, 582 protection against quinones by, 154 protection against radiation by, 634 reaction with mercurials, 129 reversal of antrycide effects by, 305 reversal of arsenical effects by, 107 reversal of mercurial inhibitions by, 132 succinic dehydrogenase and, 476 Glyceraldehyde, 552
Glyceraldehyde-3 phosphate, 136, 138, 561 Glyceraldehyde-3-phosphate
dehydrogen-ase, 452
acetylphosphate and, 132
p-chloromercuribenzoate and structure of, 136
iodoacetic acid and, 563 mercurials and, 134 Glycerol accumulation
suramin and, 292 Glycerol phosphate
teichoic acids and, 32 Glycerophosphatase
fluorine and, 360 Glycine
cell walls and, 33
Glycine—continued
ethidium bromide and, 302 extraction of enzymes and, 362 metal binding and, 121
occurrence in mucopolysaccharides, 32 purine synthesis and, 41
Glycoaldehyde
arsenite and oxidation of, 103 Glycocholate, 446
Glycocyamine, 92 Glycogen
arsenicals and, 103 radiation and, 643 Gtycollate dehydrogenase
quinones and, 152 Glycolysis
arsenicals and inhibition of, 112 arsenite and, 104
4,6-dinitro-o-cresol and, 504 polyene antibiotics and, 40 quinones and, 153 radiation and, 642, 643 reversal of, 561
reversal of arsenical effects on, 107 TEM and, 51
Glycosides
formation of, with herbicides, 258 Glycylglycine
p-chloromercuribenzoate solubility and, 127
extraction of enzymes and, 362 Glyodin, 278
respiration and, 279
spore germination and, 279, 326 Gossypin, 84
Gramacidin S
cell permeability and, 37 Gramicidin, 510, 524, 581 Grisein
iron and, 25, 47 resistance and, 29 Griseofulvin
cell wall synthesis and, 28 production in soil, 26 Growth of microorganisms
antibiotics and, 26, 31 antibiotic production and, 25 azaserine and, 41
bacitracin and, 34 chloramphenicol and, 43
Guanidine, 512 nitrification and, 621 Guanine
actinomycin effects and, 42 reversal of glyodin toxicity by, 279 structure of, 16
Guanylic acid, 181 azaserine and, 41 Hadacidin
purine synthesis and, 41 Halogens
toxicity to plants and, 338, 339 Halophenols
uncoupling by, 510 Harmaline, 73 Hela cells
actinomycin and, 30 ethidium bromide and, 302 Helium
hydrogen evolution and, 598 α-Helix of proteins
p-chloromercuribenzoate and, 138 Hematin, 480
Heme
metal ions and, 335, 336 Hemeperoxidase
iron and, 363 Hemin synthesis
radiation and, 636 Hemoglobin, 540
carbon dioxide and, 553
carbon monoxide and, 540, 543, 546 p-chloromercuribenzoate binding and,
138
metal binding and, 123 nitric oxide and, 606
nitrogen fixation and, 602, 603 sodium nitrite and, 550 solubility changes in, 362 sulfhydryl groups in, 124 Hemoglobin synthesis
manganese and, 359
"Hemolytic crisis"
copper and, 358 Hemoproteins
azide and, 396
azide complexes of, hydrogen peroxide and, 400
Hemoproteins—continued fluoride and, 404
sulfide and mechanisms of action, 406 Hemorrhagic necrosis, 464
Heparin, 451-464 Hepatoma
radiation and, 643
2-Heptadecyl-2-imidazoline—see glyodin 2 Heptyl 4 hydroxyquinoline Ν
-oxide—see HOQNO Herbicides, 243-258
auxins as, 245 cell division and, 251
chloroplast development and, 253 conversion to active compounds, 255,
256
inhibition of cell division, 249 inhibition of growth regulation, 249 metabolic inactivation, 256, 258 metabolic synthesis and, 253 metabolism by plants, 254, 258 photosynthesis and, 251
structural requirements for activity, 256 Hesperidin, 448
Hexokinase, 452 arsenicals and, 104 radiation and, 634 suramin and, 293 Hexosamine
vancomycin and, 34 Hill reaction, 584
inhibitors of, 572 phenylureas and, 251, 252 Histaminase, 58
Histamine, 58
anaphylaxis and release of, 12 N A D and, 12
l-ribosyl-4-imidazole acetic acid and, 12 structure of, 12
Histamine adenine dinucleotide, 12 Histamine adenine dinucleotide phos
phate
preparation of, 12 Histamine mononucleotide
preparation of, 12 Histidine
captan toxicity and, 281 chelation and, 378 cobalt and, 358 enolase and, 378
oxygen absorption and, 358 phosphorylation of, in aging, 224 protection against
dialkyldithiocarbam-ates, 272 Histone, 456 HN2, 164
Homoprotocatechuic acid, 69 Homovanillic acid, 69 HOQNO, 580, 584 Hyaluronate, 453 Hyaluronidase,
activation of, 61
polyanion inhibitors and, 448-460 quinones and, 149
scheme of activation and inhibition, 462 suramin and, 293
Hydantoin
nitrogen mustard derivatives of, 173 Hydrazine
ammonia oxidation and, 627 nitrogen fixation and, 608 Hydrazines, 66
Hydrazinophthalazines, 66 Hydrazoic acid, 395, 396 Hydrogen
arsenicals and activation of, 105 deadaptation and, 572
evolution of
carbohydrates and, 598 inert gases and, 598 nitrogen (gas) and, 597, 599 nitrous oxide and, 605
mercaptide agents and transfer of, 120 nitrogen fixation and, 596, 600
photosynthesis and, 571 Hydrogenase
carbon monoxide and, 610
exhaustion of nitrogen and stimulation of, 607
nitric oxide and, 606 nitrogen gas and, 597, 598 oxygen and, 604
relation to nitrogenase, 599, 600 Hydrogen peroxide
azide inhibitions and, 396 hydroxylamine oxidation and, 400 Hydrogen sulfide
nitrogen fixation and, 608 fungicidal action of, 269
comparison with sulfur, 328
Hydrogen sulfide—continued inhibitions by mercury and, 125 mechanisms of fungicidal action of, 268 0-mercaptopyruvate cleaving enzyme
and, 356 papain and, 392 photoreduction and, 572 production of
fungicidal action of sulfur and, 267 Hydrophilic groups, 438
Hydrophobic bonds, acetylcholinesterase and, 194
Hydrophobic groups, 438 D-a-Hydroxyacid dehydrogenase
oxalate and, 383
relative effects of azide and cyanide, 398 3-Hydroxyanthranilate oxygenase,
men-adione and, 152
Hydroxyapatite, fluorine and, 360 2-Hydroxy-3-butenyl-l, 4-naphthoquinone
—see lapachol
£-(4-Hydroxy butyl) -cysteine, 184 2-Hydroxy-3(2 methyloctyl)-l,
4-naphtho-quinone—see SN 5949
2-Hydroxy-l, 4-naphthoquinone, 154 0-Hydroxybutyric acid
acetoacetate formation from 6-aminonicotinamide and, 11 diethyl stilbesterol and, 11 testosterone and, 11 oxidation of,
arsenicals and, 105
6-aminonicotinamide and, 10 3-Hydroxycinnamic acid, 83, 84
5-(3-Hydroxycinnamoyl) salicylic acid, 84 5-Hydroxyindoleacetic acid, 70
tranylcypromine and, 65 Hydroxylamine, 574
acetylcholinesterase and, 200, 201 affinity for catalase, 399
enzyme inhibition and, 127
formation of, in ammonia oxidation, 626, 627
nitrite oxidation and, 626 nitrogen fixation and, 607, 608 oxidation of, 627
catalase inhibition and, 400 pyrophosphate and, 410 photoreduction and, 572 photosynthesis and, 569
Hydroxyl ions
photooxidation of, 571, 583 photosynthesis and, 574 p-Hydroxymandelic acid, 71
3-Hydroxy-4-methoxycinnamic acid, 83 Hydroxymethylschradan
cholinesterase inhibition and, 224 3-Hydroxyphenylacetic acid, 85 4-Hydroxyphenyllactic acid, 84 3-Hydroxyphenylpropionic acid, 84 3-Hydroxyphenylpyruvic acid, 84, 85 3-Hydroxyphenyltrimethylammonium ion,
197
m-Hydroxypropadrine, 87 8-Hydroxyquinoline—see oxine
3 - Hydroxytetrahydrothiophene 1,1-di-oxide, 185
Hydroxytyramine, 79
3-Hydroxytyramine—see dopamine 5-Hydroxytryptophan, 63
Hypnotic power
respiratory inhibition and, 519 Hypochlorite
toxicity to plants, 338 Hypoglycemia
trypanosome metabolism and, 294 Hyponitrous acid, 605
Hypoxanthine
molybdenum and liver content of, 354 sulfide oxidation and, 357
structure of, 16
Hypoxanthine adenine dinucleotide imidazole adenine dinucleotide and, 11 Hypoxanthine mononucleotide—see
ino-sinic acid
IAA—see 3-indole acetic acid IAN—see indole acetonitrile Imidazole
mercury binding and, 125 metal binding and, 121
Imidazole adenine dinucleotides, 12 NAD'ase and, 11
3-(a-Iminoethyl)5-methyl tetronic acid chlorosis and, 253
Indole-3-ethylamine—see tryptamine Indoleacetaldehyde, 69, 70
radiation and conversion to indoleace-tate, 641
Indoleacetamide auxin activity of, 255
formation from indoleacetic acid, 257 Indoleacetic acid
CoA derivative of, 248 conjugation of, 257 decarboxylation of, 257 formation of, from nitrile, 255 identification of, 245
maleic hydrazide and action of, 249 methylation and, 247
oxidation of, 257 citrate and, 410 pyrophosphate and, 409 radiation and formation of, 641 structure of, 246
Indoleacetic acid oxidase
2,4-diehlorophenoxyaeetie acid and, 257 maleic hydrazide and, 249
Indoleacetonitrilase, 255 Indoleacetonitrile
breakdown of, 255 Indoleacetylaspartic acid
CoA and formation of, 248
formation from indoleacetic acid, 257 Indoleacetylglycine, 257
Indolebutyric acid
CoA and oxidation of, 248 Indolecarboxylic acid, 255 Indolepropionic acid
oxidation of citrate and, 410 pyrophosphate and, 409
Indophenol oxidase—see cytochrome oxi-dase
Infertility
ethylenimines and, 178 TEM and, 178
INH—see isonicotinyl hydrazide INH-AD—see isonicotinyl hydrazide
ade-nine dinucleotide Inosinic acid
hadacidin and adenylosuccinic acid syn-thesis and, 41
imidazole adenine dinucleotide and, 11 synthesis of
azaserine and, 41 Insulin, 441
detergents and, 443
trypanosome multiplication and, 294 zinc binding and, 123
Insecticides
organophosphates, carbamates and, 206 Interfacial tension, 438
Intrinsic viscosity
p-chloromercuribenzoate and, 138 protein structure and, 136 Invertase, 447
radiation and, 635 SDS and, 442 Iodide
affinity for mercury and, 122
estimation of sulfhydryl groups and, 135 mercaptide formation and, 128
toxicity to plants, 338, 339 Iodine
animal requirements, 312 Iodoacetamide
phosphoribulokinase and, 563
reaction with sulfhydryl groups and, 146 Iodoacetic acid
alcohol dehydrogenases and, 103 glyceraldehyde-3 phosphate
dehydroge-nase and, 137, 138 nitrogen fixation and, 608, 609 photosynthesis and, 563
reaction with sulfhydryl groups, 146 succinic dehydrogenase and, 481 transaminases and, 105
Ion antagonism, activity coefficient and, 316
Ionization, toxicity of carbamates and, 215, 216
Ions
activation and inhibition of enzymes and, 363, 364
affinities for specific groups chelation and, 374, 375, 377, 378
enzyme activity and, 371-375, 377, 378
alkali metals, 342, 343 antagonisms of, 314, 318 as essential elements, 312
chelation of and enzyme activity, 408, 410
chlorophyll synthesis and, 329, 330 bicarbonate and, 337
chelation and, 331, 332 nitrogen nutrition and, 334
stability constant of metals and, 333
Ions—continued enzyme activity and
alternative activating metals and, 364, 365
competition by inactive metals, 369, 371
competitive inhibition and, 368-371 enzyme reactions and, 361-420 extraction of enzymes and, 362 fluoride effects and, 403 fumarase and, 380
growth and chelation of, 318, 319, 324 in proteins
reaction with sulfide, 406, 407 kinetics of enzyme reactions and, 375,
376
metalloenzymes and, 383, 390, 403, 405 reaction with proteins, 361
selenosis and, 350, 351
synthesis of hematin enzymes and, 336 toxicity of
chelates and, 379
factors involved in, 327, 328 fungi and, 325, 326
physicochemical character, 324, 325 toxicity to animals, 349-360, 363 toxicity to higher plants, 328, 349 toxicity to plants, 341, 342
aluminum and, 341, 342
halogen derivatives and, 338, 339, 340 uncompetitive action of, 382, 383 IPC—see isopropyl iV-phenyl carbamate Iproniazid, 62, 64, 65, 70, 73
action of, 66
conversion to isopropylhydrazine, 73 hydrolysis of, 66
lathyrism and, 68
monoamine oxidase and, 90 reserpine and, 71
Iron
aldolase and, 369 chelation of, 271, 372
chlorophyll synthesis and, 329, 330, 335 complex with tetracycline, 324
deficiency of
bicarbonate and, 337
chlorophyll synthesis and, 329, 330 diethyldithiocarbamic acid toxicity and,
323
enzyme inhibitions,
solubility product and, 372
fungicidal action of, 265 grisein synthesis and, 25 growth requirements for, 314 hemeperoxidase and, 363 nitrite oxidation and, 625 oxine toxicity and, 321
protoporphyrin accumulation and, 335 protoporphyrin synthesis and, 336 sideromycins and, 47
toxic effects of metal ions and, 318 toxicity of oxine complex, 321 tryptophan synthetase and, 376 uptake of, 334
Iron sulfate
weed killing action of, 244
I.S.2596—see N'-(l, 4-benzodioxane-2-methylJ-W-benzylhydrazine
3-Isobutyryl pyridine, N A D analogues of, 9
Isocarboxazid, 67, 69 Isocitratase, 490 Isocitric dehydrogenase
alternative activating metals and, 364 cobalt and, 336
comparative effects of metal ions and, 368
inhibitors of, 495 steroids and, 495 Isoelectric point
detergent effects at, 440, 441 solubility of proteins and, 362 values of, 447
Isoferulic acid, 83, 84 Isolan
structure of, 208 toxicity of, 215
Isoniazid—see isonicotinyl hydrazide Isonicotinic acid, 67
1-Isonicotinic acid 2-isopropyl hydrazide—
see iproniazid
1-Isonicotinoyl-l-methyl hydrazine chelation and, 323
Isonicotinyl hydrazide, 57, 68 antitubercular action of, 7 combination with pyridoxal, 324 dinucleotide synthesis and, 6 histamine release and, 12 Μ. tuberculosis and, 325 nucleic acid synthesis and, 7
replacement of nicotinamide by, 324 structure of, 7
Isonicotinyl hydrazide adenine dinucleo
tide action of, 6
antitubercular activity and, 7 synthesis of, 6
Iso-OMPA
see JVjiV'Diisopropyl phosphorodiami-dic anhydride
Isopropyl iV-(3-chlorophenyl) carbamate cell division and, 251
Isopropylhydrazine, 67 Isopropyl iV-phenyl carbamate
cell division and, 251 4-Isopropyltropolone, 91 Isoproterenol, 87 Isosteric residues, 54 Isothiocyanates
formation from ethylenethiuram mono
sulfide 274 Isoxazolidones, 87 Itaconic acid, 487, 494 Jensen sarcoma
arsenite effects on, 104 Kainite, 244
Karsil—see N- (3,4-dichlorophenyl) -2-methyl pentanamide
Kerateine
binding of arsenicals by, 108 sulfhydryl groups in, 108 Keratin development
selenium and, 350 α-Keto acids
arsenicals and oxidation of, 103, 110 cytochrome c reductase and, 382 lipoic acid and, 110
α-Ketoglutaric acid
arsenicals and synthesis of, 103 citrate formation from
6-aminonicotinamide and, 11 hormones and, 11
dialkyldithiocarbamate-zinc salt and, 270
oxidation of, 495
6-aminonicotinamide and, 10 arsenite and, 110
lipoic acid and, 110 transamination and, 45
α-Ketoglutaric dehydrogenase cadmium and, 377
Kinetin, 248 Kinetoplast, 301, 302 Kinins, 245
Kojic acid, 323 Krebs ascites
radiation and glycolysis of, 643 Laccase
cyanide and, 389 sulfide and, 407 Lachrymators, 482
Lactation tetany, manganese and, 359 Lactic dehydrogenase
6-aminonicotinamide and, 10 arsenite and, 104
kinetics of mercaptide formation and, 130
mercaptide formation and, 131 mercury complex of, 125 SDS and, 443, 462, 463
Lactobacillus arabinosus, ion requirements of, 313
Lactobacillus casei ion requirements of, 313 potassium requirements of, 315 Lactobacillus leichmanii, ions and growth
of 312
Lactogenic hormone, 443 /3-Lactoglobulin, 439, 441, 456
mercaptide formation and. 131
3-O-Lactyl-D-glucosamine—see muramic acid
Lakeseal, 441
Lameness, selenium and, 350 Lapachol
inhibition of oxidative phosphorylation by 156
structure of, 155
succinate oxidase and, 154 Latent activity, 172 Lathyrism, 68 Lead
binding of, 121 cell division and, 349 plant growth and, 347, 348 Lecithin, 94
Lecithinase, SDS and, 442