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K A J R O H O L M

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DEDICATION: TO THE MEMORY OF KAJ ROHOLM

(October 7, 1902-March 29, 1948)

Roholm's monograph on "Fluorine Intoxication/' a classic in the field, dominates the literature on the biological effects of fluorides and historically divides knowledge on this subject into two periods—the work prior to 1937, the year his monograph appeared, and the work since.

His summaries are so informative and so clearly organized that, where appropriate, the tables of our chapters follow his format precisely. Many concepts that he suggested (often on incomplete data) now can be sub­

stantiated in fuller detail as a result of the large number and diversity of research reports published in the intervening nearly 30 years. Although our own studies are only incidentally described herewith (in contrast with the extensive original data comprising much of his monograph), we hope that we have caught some of his enthusiasm and that we have added a few generalities. Certainly, few modern public health practices potentially affect so many people as does fluoride's ability to decrease dental decay.

It is sad that Roholm's untimely death brought to an end his expert contributions to fluoride toxicology at a time when questions of the safety of fluoride exposures, in industry and in public health, hold such public interest and importance.

A native of Copenhagen, Kaj Roholm displayed as a student the brilliance characterizing his later professional life. Soon after completing his medical studies with first honors at Copenhagen University in 1928, he began the active scientific life that distinguished his career. His first studies with Knut Faber and Hess Thaysen dealt with the mechanism of gastric secretion and the influences thereon of insulin and adrenaline, foreshadowing his later clinical interests in the gastrointestinal tract. His interest and training in public health (Master of Public Health, 1933) led to service with the Copenhagen City Health Commission, first, as an assistant in Public Health from 1935 to 1937, and later, as Deputy Health Officer from 1940 until his death. His thesis for his M.D. degree (1935),

"Fluorine Intoxication," was written under the direction of Professor Fridericia of the Hygienic Institute whom Roholm was destined to succeed.

As a public health officer, Dr. Roholm effectively and enthusiastically campaigned for preventive medical measures designed to eliminate such scourges as diphtheria and venereal disease. He employed modern tech­

niques and modern media—films, radio, posters, brochures. He had the

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viii DEDICATION TO THE MEMORY OF KAJ ROHOLM

gift of a pithy, popular style; during the occupation, for example, some 600,000 copies of his pamphlet on "What Everyone Wants to Know Today About Infectious Diseases" were distributed.

His memberships on committees, commissions, and societies include the Society for Health Care, The Younger Doctors' Committee for Con­

tinuation Courses in Socialized Medicine, The Danish Association for the Prevention of Venereal Disease, a Committee to Organize a Permanent Hygiene Exhibition, and the Pharmacopeial Revision Committee.

After Fridericia's early death, Roholm was named Professor in recogni­

tion of his wide acquaintance with and interest in practical community health problems. His first lecture revealed his rich talents as he made the material become alive and fascinating. His pale appearance gave warning of a deep-seated illness ; his first lecture was his last. He entered the hospital and died a month later, the victim of a cancer of the large bowel.

Kaj Roholm left memories of a talented and vigorous scientist, a devoted and dedicated clinician and public health officer, and a genuine and gracious human being.

These chapters on the biological effects of fluorides are dedicated to Professor Roholm, acknowledging our own indebtedness to him and hoping that, in this way, his many contributions will be recognized by those who labor for the cause of public health.

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