Abstracts 530–579
530 C Site-Specific Intercalation of Doxorubicin Disrupts the Iron-Responsive Element RNA – Iron Regulatory Protein Interaction
Luigi Alvarado, Kyle Eggleston, Sam Lin, Virginia Smith, Adegboyega Oyelere, Kwaku Dayie 531 A Defining a eukaryotic core mRNA interactome: the landscape of RNA-binding proteins in yeast
and its conservation in mammals
Benedikt Beckmann, Alfredo Castello, Bernd Fischer, Rastislav Horos, Claudia Strein, Katrin Eichelbaum, Sophia Föhr, Thomas Preiss, Lars Steinmetz, Jeroen Krijgsveld, Matthias Hentze 532 B Regulation of human telomerase by the helicase RHAU, a quadruplex resolvase.
Evan Booy, Markus Meier, Trushar Patel, Ryan Howard, Natalie Okun, Oksana Marushchak, Jörg Stetefeld, Sean McKenna
533 C In vivo dynamics of SR protein-RNA interactions
Serena Capozi, Eugenia Basyuk, Antoine Cléry, Frédéric Allain, Edouard Bertrand 534 A GOLLD: a large, structured, noncoding RNA from bacteria and bacteriophages
Andy Chen, Ronald Breaker
535 B Dynamic transition upon protein-RNA complex formation: PTB RRM1 interaction with an IRES stem-loop
Fred F. Damberger, Christophe Maris, Frédéric H.-T. Allain, Sapna Ravindranathan
536 C AURA 2.0: empowering post-transcriptional regulatory networks discovery
Erik Dassi, Toma Tebaldi, Angela Re, Sara Leo, Daniele Peroni, Luigi Pasini, Alessandro Quattrone 537 A The QUA2 domain of GLD-1 recognizes an additional nucleotide and modulates RNA binding
affinity
Gerrit Daubner, Stefan Gerhardy, Frédéric Allain
538 B Control of Mammalian Germ Cell Differentiation by the RNA-Binding Protein DAZL Renaud Desgraz, Katherine Romer, David C Page
539 C Structural and Dynamic Investigation on ETR-3 RRMs and their Interaction with AU-rich RNAsNana Diarra dit Konte, Frederic Allain
540 A Interactions between RBFOX2 and pre-microRNA-20b terminal loop
Afzal Dogar, Julian Zagalak, Moritz Stoltz, Harry Towbin, Michel Erich, Frédéric Allain, Jonathan Hall
541 B RNA-binding protein EWSR1 regulates CCDC6
Sujitha Duggimpudi, Erik Larrson, Arndt Borkhardt, Jessica Hoell
542 C Dead End, a protein counteracting miRNA-mediated repression of tumour suppressor genes, contains non-canonical RNA binding domains
Malgorzata Duszczyk, Frédéric Allain
543 A Potential substrates of the RNase MRP complex in cell cycle regulation
Franziska Eckmann, Anika Wehrle, Anika Salfelder, Romy Keppler, Ekkehart Lausch, Bernhard Zabel 544 B Post-transcriptional regulation of SMN2 expression by hnRNP G and LARP Family proteins
Ana Miguel Fernandes, Ana Luísa Gomes, Mariana Oliveira, Gonçalo Costa, Isabel Peixeiro, Ana Margarida Matos, Carlos Cordeiro, Margarida Gama-Carvalho
545 C Characterization of the potential role for RNA-binding protein FUS/TLS in DNA damage response: A quantitative proteomic approach
Giuseppe Filosa, Marc-David Ruepp, Carolina Lenzken, Alessia Loffreda, Oliver Mühlemann, Angela Bachi, Silvia Barabino
546 A A novel PAR-CLIP based approach using RRM mutations reveals RNA recognition mechanisms of HuR
Matthew Friedersdorf, Jack Keene
547 B The Runt domain of AML1 (RUNX1) binds a sequence-conserved RNA motif that mimics a DNA element
Junichi Fukunaga, Yusuke Nomura, Ryo Amano, Yoichiro Tanaka, Taku Tanaka, Yoshikazu Nakamura, Gota Kawai, Tomoko Kozu, Taiichi Sakamoto
548 C Predicting RNA-Protein Interactions: The Hunt for the Code of Recognition Christian Garde, Jan Gorodkin, Christopher T. Workman
549 A Testing Protein Sequestration Candidates for RNA-Mediated Disease Marianne Goodwin, Apoorva Mohan, Maurice Swanson
550 B Computational study of interactions between amino acids and nucleobases in aqueous solvent Matea Hajnic, Juan Osorio Iregui, Thomas Malzac, Bojan Zagrovic
551 C Codon-usage effects and functional characterization of physicochemical complementarity between mRNA and cognate protein sequences
Mario Hlevnjak, Lily Chan, Anton A. Polyansky, Bojan Zagrovic
552 A Establishment of a Fluorescence Cross Correlation Spectroscopy (FCCS) based assay to measure Argonaute – siRNA interaction
Leonhard Jakob, Michael Hannus, Stefan Hannus, Gunter Meister 553 B Post-transcriptional control of macrophage activation by HuR.
Panagiota Kafasla, Orsalia Hazapis, Martin Reczko, Dimitris Kontoyiannis
554 C Repetitive RNA unwinding of a single RNA helicase A Hye Ran Koh, Li Xing, Lawrence Kleiman, Sua Myong
555 A The RNA-binding Protein Repertoire of Embryonic Stem Cells
S. Chul Kwon, Hyerim Yi, Katrin Eichelbaum, Sophia Föhr, Bernd Fischer, Kwon Tae You, Tuan Anh Nguyen, Alfredo Castello, Jeroen Krijgsveld, Matthias W. Hentze, V. Narry Kim1
556 B Drosophila Gemin5 binds to UsnRNAs and another specific group of ncRNAs Sheila SK Li, Jonathan PY Lau, Tinyi Chu, Brian Qin, Ting-Fung Chan, Terrence CK Lau 557 C RBP atlas: an exploration of interactions between mRNA and proteins and their impact on
cardiomyocyte biology
Yalin Liao, Alfredo Castello, Sophia Foehr, Stefan Leicht, Rastislav Horos, Jeroen Krijgsveld, Matthias Hentze, Thomas Preiss
558 A Multifunctional interleukin-6 receptor aptamers Eileen Magbanua, Ulrich Hahn
559 B Neurodegenerative diseases: quantitative predictions of protein-RNA interaction Domenica Marchese, Davide Cirillo, Gian Gaetano Tartaglia
560 C RNA helicase function in yeast ribosome biogenesis
Roman Martin, Philipp Hackert, Maike Ruprecht, Stefan Simm, Enrico Schleiff, Markus Bohnsack 561 A Knock-out mice and HITS-CLIP reveal that the SGs assembly factor G3BP preferentially binds
intron-retaining transcripts and controls their stability in the brain
Sophie Martin, Juan Gonzáles-Vallinas, Nicolas Bellora, Manuel Irimia, Latifa Zekri, Alexandra Metz, Karim Chebli, Michel Vignes, Eduardo Eyras, Javier F Caceres, Ben J Blencowe, Jamal Tazi 562 B A co-evolution network of binding contacts between protein L25 and 5S rRNA
Zhichao Miao, Eric Westhof
563 C Mechanism of action of the CCCH zinc finger protein TbZC3H11 upon heat shock Igor Minia, Dorothea Droll, Aditi Singh, Christine Clayton
564 A Sequence specific code in RRM–RNA interactions
Martyna Nowacka, Stanislaw Dunin-Horkawicz, Kama Wojcik, Janusz Bujnicki
565 B Regulation of mRNA metabolism by U2AF65 splicing factor - novel mechanisms for the coordination of gene expression?
Isabel Peixeiro, Samuel Casaca, Margarida Gama-Carvalho
566 C Division of labor: separation of loading and unwinding units in an oligomer of the DEAD-box helicase Ded1p
Andrea Putnam, Huijue Jia, Fei Liu, Eckhard Jankowsky
567 A Manipulating endogenous RNAs with synthetic RNA-binding proteins
Oliver Rackham, MF Razif, KK Nygård, TS Chia, ME Hibbs, SM Davies, I Small, A Filipovska 568 B Imbalance of Zfp36l2-RNA-binding protein results in female infertility
Silvia Ramos
569 C Structure-specific RNase footprinting in multiple cell types reveals protein-binding sites throughout the human transcriptome
Ian Silverman, Fan Li, Anissa Alexander, Daniel Beiting, Nur Selamoglu, Fevzi Daldal, Brian Gregory
570 A Architecture of catalytic complexes essential for synthesis and co-translational insertion of selenocysteine in humans
Miljan Simonovic, Rachel Schmidt, Malgorzata Dobosz-Bartoszek
571 B hnRNP A1 Interacts with Conserved RNA IRES Elements in Enterovirus 71 Michele Tolbert, Jeffery Levengood, Mei-Ling Li, Blanton Tolbert
572 C Human DIS3L2 exonuclease is involved in the processing of tRNA-derived small RNAs
Dmytro Ustianenko, Biter Bilen, Katerina Chalupnikova, Zuzana Feketova, Georges Martin, Mihaela Zavolan, Stepanka Vanacova
573 A HIV Nucleocapsid Protein Precursors are Effective Nucleic Acid Chaperone Proteins Wei Wang, Mithun Mitra, Robert Gorelick, Zhengrong Wu, Karin Musier-Forsyth
574 B Tethered Domains and Flexible Regions in tRNase ZL, the Long Form of tRNase Z Christopher Wilson, Emmanuel Chang, Louis Levinger
575 C Poly(A) binding protein 1 and formation of processing bodies in human Jingwei Xie, Guennadi Kozlov, Kalle Gehring
576 A Crystal structure of the active conformation of the Shigella flexneri VapC toxin at 1.9 Å resolution
Kehan Xu, Emil Dedic, Patricia Cob-Cantal, Christian Dienemann, Andreas Bøggild, Kristoffer S.
Winther, Kenn Gerdes, Ditlev Brodersen
577 B Alanine scanning of the aa-tRNA binding interface of Escherishia coli EF-Tu Emine Yikilmaz, Olke Uhlenbeck
578 C Evidence of direct complementary binding between mRNAs and cognate proteins Bojan Zagrovic, Mario Hlevnjak, Anton Polyansky
579 A Responses of the mRNA interactome to genotoxic stress
Elisabeth Zielonka, Alfredo Castello, Benedikt Beckmann, Rastislav Horos, Anne-Marie Alleaume, Claudia Strein, Sophia Foehr, Bernd Fischer, Jeroen Krijgsveld, Matthias Hentze