Despite the valuable contributions that have been made by means of experimental animals to the present understanding of the utilization of proteins and amino acids, the danger that is inherent in extrapolating from other species to man should be recognized, particularly if data obtained from a growing animal are applied to the adult. Since Mitchell
(92) has reviewed species differences in amino acid requirements, two illustrations will suffice here. Cox et al. (52) reported that lactalbumin and casein were similar in biological value for man, whereas the former is distinctly superior for the rat with its proportionately higher demand for sulfur-containing amino acids. The satisfactory utilization of glycine and the deleterious effect of diammonium citrate in man contrast sharply with observations in young rats and chicks (80). Additional in
formation concerning the fundamental laws which govern the utilization of amino acids is needed for all species, but especially for man to whom the quality and quantity of protein is of vital importance.
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