Meanwhile, they have revealed a so far hidden complexity of the herpesvirus transcriptome with the discovery of a large number of novel RNA molecules, including coding and

In processes known as RNA interference (RNAi) and microRNA (miRNA) mediated silencing, Argonaute proteins associate with small non-coding RNAs and use them as guides to bind

Non-coding RNA molecules encompassing microRNAs, long non-coding RNAs, and circular RNAs have been implicated in the pathogenesis of various tumors, and were also proposed as

VCM – Invariants • There is at most one Leader > After the Leader gets stuck, the Leadership is transferred • Followers only follow their predecessor > Predecessor is either in a

We identified and annotated altogether 132 novel transcripts and transcript isoforms, including 4 coding and 4 non-coding RNA molecules, 47 length variants, 5 splice isoforms, as

Interestingly, the percentage of arginine residues within positively charged ones defined as 100*N R (N R +N K ) (where N R represents the number of arginine and N K the number

MicroRNAs (miRNA, miR) are short – 19–25 nucleotide long – single stranded (in their mature form), non-coding RNA molecules that regulate gene expression mostly at

Klivényi, Increased level of NEAT1 long non-coding RNA is detectable in peripheral blood cells of patients with Parkinson’s disease, Brain Research (2020),

While we did detect increased expression levels of Malat1 in ischemic kidney biopsies and plasma of patients with AKI, ischemic mouse kidneys and sorted endothelial cells and

In non-small-cell lung carcinoma, the anti-sense transcript of the tumor suppressor in lung cancer 1 (TSLC1) RP11-713B9.1 was shown to be downregulated, and its functions as

To further validate the functionality of the in  silico predicted and in  vitro determined IL-6 mRNA interacting region in the PRINS sequence, we performed the

For example, in municipalities that also hold elections at local level, and where additional thresholds are imposed – such as a required number of registered voters or group

Expression analysis of exosomal long non-coding RNAs H19 (A), HOTTIP (B), HULC (C) and MALAT1 (D) in two independent cohorts (cohort 1, left panels, cohort 2, right panels) in

Their highly cooperative and pioneering work in pyknon and long non-coding RNA (lncRNA) research (1) indicates the role of the novel pyk-reg-90- containing lncRNA,

MicroRNAs (miRNAs) are 18–25 nucleotide long, single stranded, endogenous, non-coding small RNAs playing an important role in regulating gene expression at posttranscriptional

Alfr´ ed R´ enyi Institute of Mathematics, PO Box 127, H-1364 Budapest, Hungary, and Department of Mathematics, University College London, Gower Street, London, WC1EF.

Here, we performed deep sequencing-based extensive analysis of transcriptomic changes in cSCC, which allowed us to identify differentially expressed protein-coding genes,

Using this information, we have annotated 291 previously undescribed or only partially annotated transcript isoforms, including eight novel antisense transcripts and their