Development of Complex Curricula for Molecular Bionics and Infobionics Programs within a consortial* framework**
Consortium leader
PETER PAZMANY CATHOLIC UNIVERSITY
Consortium members
SEMMELWEIS UNIVERSITY, DIALOG CAMPUS PUBLISHER
The Project has been realised with the support of the European Union and has been co-financed by the European Social Fund ***
PETER PAZMANY CATHOLIC UNIVERSITY SEMMELWEIS
UNIVERSITY
Organic an Biochemistry
The main classes of compounds and their reactions
www.se.hu
(Szerves és Biokémia )
(A legfontosabb reakcióink és vegyülettípusaink)
Compiled by dr. Péter Mátyus
with contribution by dr. Gábor Krajsovszky
Table of Contents
semmelweis-egyetem.hu
Organic and Biochemistry: Reactions and Compounds
1. Alkanes 4 – 5
2. Alkenes 6 – 7
3. Alkynes 8 – 8
4. Arenes 9 – 9
5. Aryl diazonium compounds 10 – 10
6. Alkyl halides 11 – 16
7. Alcohols 17 – 23
8. Oxo compounds 24 – 26
Alkanes Alkenes
Carboaromatics Alkyl halogenides Alcohols
Ethers
Reactions – Transformation of functional groups I
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
Alkane – alkyl halogenide
Organic and Biochemistry: reactions and compounds
semmelweis-egyetem.hu
Alkenes Alkanes Alcohols
Ethers Organometallic
compounds
Esters
Thiols Amines
Nitriles Alkylated products
Alkenes Organometallic Primary
Alkyl
halides
Alkyl halogenide - alkane
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
C Br H
C H H Bu
3SnH
AIBN
Br
Bu
3Sn Bu
3SnH
+ Bu
3Sn
AIBN = azobisisobutyronitrile
Alkenes (olefines)
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
Alkenes
Alkanes Alkyl halides Alcohols
1,2-Dioles Alkynes
Aldehydes
and ketones Amines Epoxides Halohydrins
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
C C C
H
E
+reacts with electrophiles (Markownikoff addition) and radicals
carbocations and radicals delocalized and stabilized by the adjecent double bond reactions with dienes in
Diels-Alder reactions
Alkynes
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
Alkynes
Alkanes Alkenes
Dimers, trimers and tetramers
Alkyl halides Ketones
Ethynyl alcohols
Organometallic
compounds
Aromatic compounds
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
Arenes
Arylamines Aryl halides
Aryl carboxylic acids
Aryl aldehydes and ketones
Arylalkanes
Aryl diazonium compounds
Aryl
nitro compounds
Aryl sulfonic acids
Phenols Quinones
Amides Imines
Aryl diazonium compounds
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
Aryl diazonium compounds
Arenes Phenols Aryl nitriles
Aryl fluorides Aryl halides (Cl, Br, I) Arylamines
Diazo compounds
Aryl hydrazines
Alkyl halogenides
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
H C
C halogen elimination
nucleophilic substitution
metal insertion
radical attack
Organic and Biochemistry: Reactions and Compounds
semmelweis-egyetem.hu
Me
C Cl Me
Me C+
Me
Me Me Me
C OH Me
Me
+
Me C O H
Me
Me
+
Cl-slow H2O
Me (CH2)2
CH3 O
H -
Me (CH2)2
CH2 Cl OH
-
Me(CH2)2 CH2 O
H
+
Cl-Me
C Br Me
Me C+
CH2
Me Me H
slow O H -
C CH2
Me Me
- H CH CH
CH3
Br